Well, it doesn't sound good. You might want to try something I have discovered works really well after my guinea died from the antibiotics given to him. I spent tons of money on vets, never again. Sovereign Silver is a natural antibiotic sold at health food stores, as well as online. It is also used as an immune booster and treatment for various illnesses. It has been used in humans and pets for years with great success. Recently, it has not been used as much in humans because of a few people turning blue from applying directly to their skin (which you are not supposed to do) or overdosed daily for over 70 years. Toxicity is virtually impossible, and it always works you just have to figure out how much to give. Normally, I start at first symptoms such as runny nose or sneezing and wheezing. 6 drops morning and 6 drops night, along with 2 nasal squirts in each nostril (it comes in nasal spray too). Doing both helps prevent your guinea pig from expelling it all. Sometimes I find that my guinea pigs are not swallowing so I do only nasal sprays, several every hour, for sinsus or respiratory things. If you feel symptoms are severe or very sure of infection do this 6 drops every hour with 2 nasal sprays. No worries because you don't have to worry about your guinea pig turning blue. It does say it can effect the good bacteria, but I doubt it. However, I always give my guinea pigs probiotics during this time. I mix 1/2 a capsule of probiotics in chamomile tea and give it to them with a dropper. They love chamomile tea so I don't have any problems getting them to drink. Normally, I do this twice a day when I feed them their fresh foods. They tend to like room temperature tea though. It saves vet bills and works without the worry of toxicity. It has been used to help lots of pets with cancer and more. Tea Tree Oil is also great for any skin problems such as mites, fungus, etc.