I was interested to read this as my Biscuit had a similar issue a year or so ago. She developed the V shaped mark/hair loss but the vet the piggies were then registered with didn't think it was anything to worry about and as an inexperienced first time piggy owner I took their word for it. It didn't seem to bother her at all. I never saw her scratching it and she let me touch it without reacting. I had a couple of conversations with the vet nurse later when I took the piggies in to have their nails clipped and she also said that she didn't think it was mites, though after speaking to the vet she said they would give her and Toffee a dose of ivermectin 'just in case'. (Yes, just one dose!)
However as time went on the mark didn't go away and I'd begun to get worried again and wanted a second opinion. After a few phone calls I was lucky enough to find a lovely vet practice with an experienced exotic vet who agreed to see her. The vet immediately said that Biscuit had Hay Mites (not Mange Mites) and treated both her and Toffee with Xeno 450 explaining (as I already knew) that they would need two further doses 7-10 days apart. Sure enough this did the trick and Biscuit's fur grew back beautifully. At no time did her cage mate Toffee seem to be affected.
I still feel stunned that the original vets, while very nice, seemed totally clueless when it came to guinea pigs.