Guinea pigs do not get colds. They get bacterial respiratory infections which need to be treated with antibiotics.
If the antibiotic isn’t the right one, or the course isn’t long enough then some bacteria can remain and set them off feeling unwell again.
What antibiotics were you given previously and how long were the courses each time?
He must see a vet straight away, particularly if his breathing is slowing. Upper respiratory infections can be very serious and need treatment.
Vitamin c deficiency is rare in guinea pigs, it of course can happen. Hay and grass (which is their natural diet) contains vitamin c, their pellets are fortified with vitamin c and they should have a vitamin c rich veg each day. Therefore, a piggy on a balanced health diet does not normally have vitamin c problems. A poorly piggy can be given a short course of supplementary vitamin c to boost the immune system. If we see vitamin c deficient piggies on here. (which is not very often at all) it can be down to piggies routinely being given supplementary vitamin c products as routine . Their bodies become used to it and then if the level drops below which their body has been accustomed to, they develop vitamin c deficiency symptoms (even if the level is normal to any other piggy).
Please do not give your guinea pig anything that has not been prescribed by a vet.
Eyes are classed as urgent and if this is something unrelated to the URI then a vet needs to carry out a proper examination and prescribe the correct treatment. Eye crustyness can sometimes be related to a URI.