I've had my little ones about 7 weeks now, neither are really keen on being picked up, but once picked up both calm a little, my little boy is a lot more confident and now sits with me for a while, he'll eat on my knee, let me brush him, trim him and do his nails (though I am still nervous about the nail trimming!) then he wants to start looking around, or making a fuss as he wants a wee - I have learned this noise! I tend to let them out in my kitchen and sit on the floor and he comes over and have a run around me, my little girl is a lot shyer, she'll come up to me when I'm sat on the floor, but just freezes when i pick her up, so I only do it for a few minutes each day and when I pop her back in the cage she generally get a bit of lettuce or something, last night though I popped her on my knee on her fleece and she did seem to settle, I have to pick them up most days to pop them outside, but they do run away. I am just going to take it a day at a time, I have read that it can take a long time for some little piggies.