My girls are on fleece. I use a layer of towels on the bottom with a layer of fleece on top. There isn't a designated piddle spot anymore than with litter (though they have their preferences). The fleece wicks the moisture away from the piggy, and the towels beneath absorb it. Some people like to have the absorptive layer built into their fleece liners, but we like the layered approach. (1. It was easy to make. 2. The fleece is easy to brush and shake hay and poo off of.) I don't use a hay tray; they just get handfuls of hay added in a pile.
I used to use CareFresh, but it tangled in Lexa's fur, got all over the room, and was getting pretty expensive (and with less quality control), so I switched. Both the girls and me are pleased with the switch.