My piggy who has Interstitial Cystitis currently takes 1.2ml Loxicom 2x a day. She used to be on 1.4ml 2x a day. My piggy weighs 1.35kg though. Our guinea pig vet said that she can take 1ml/1kg depending on how it's needed. We do try out to lessen or tweak the dosage though to see at which dosage she would feel comfortable. She managed to get to 0.8ml 2x a day during the past week but she had a really bad weekend with pain, to the point that she completely stopped eating, hence we put the dosage back up again. Ask your vet regarding dosages and such to make sure you are giving your piggy the right amount.