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Specialist Guinea pig not eating and lethargic after anti fungal medication

amber89

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Hello all,

I am having 3 guinea pigs at home. All 3 of them are being treated for a parasitic infection with Stronghold 15mg ( in German, they are treated for Haarlinge, in English i think they are called Chewing lice ). In addition to Stronghold, all 3 of them are receiving VAPOVIT (Korvimin Vapovit), one spray each of them on one slice of cucumber, daily.

In addition, one of them (Muffin) was diagnosed on Thursday with a fungal infection. Two days before her diagnosis she was already separated from the others due to a (possible) bond fallout. Initially she was kept on the upper floor of the cage, without the possibility of seeing the other 2 piggies. Fron Thursday on, the cage setting was altered so that she can interact with the others via a grill divider. She also started immediately her treatment with PROGRAM 133mg Suspension for cats (CPT: CliniPharm/CliniTox).

The morning after, meaning on Friday, i noticed that she was just lying in her cage and didn't react when i announced the first feeding of the day. She was refusing any food, including hay, lettuce, paprika or cucumber. My husband rushed with her at the vet and she received an injection for perking her up and for at home she received NUX VOMICA (https://www.heel.de/media/de/downloads_pdf/heel_de_1/gebrauc ... 5825_bpz.pdf). The vet meant that her lack of appetite might be an adverse effect of the anti-fungal meds. Around 1h after the vet visit she was started to feel better and for the rest of the day she was happily eating her hay and veggies. Friday evening she got another dosis of NUX VOMICA and we went to bed.

Saturday morning she was again extremely lethargic and refusing all food. We gave her again the dosage of NUX VOMICA and waited for her to get better and start eating. By 12 PM she was not feeling better and she barely ate half of a Cos lettuce leaf. We rushed with her at the vet again (unfortunately not our usual vet, because she was on Easter holiday already). The other vet said that she is a bit bloated and that teeth problems can"t be ruled out. We were given COLOSAN for her bloating (ColoSan® - Dr. Schaette) and RODICARE akut (RodiCare akut) & instant (RodiCare instant für Nagetiere und Kaninchen) for hand feeding her. From Saturday afternoon we started syringe feeding her RodiCare Instant every 3.5h and giving her some lettuce (lollo rosso, cos, escarole). Over 24h we managed to feed her around 60-70 ml of RodiCare instant.

We also started tracking her weight more thoroughly: on the 18th she weighted 1002g; on the 20th she was only 980g and on the 21st, with all our feeding she lost even more to 969g. In the evening of the 21st, we weighted her again and she finally managed to recover some lost weight, reaching 989g. This morning she was at 995g, but, by 4 PM she lost another 10g.

Starting with Saturday evening she finally started taking small steps around her enclosure, drinking water by herself and nibbling some 2-3 hay straws. Also, she started eating her own poo and cleaning herself. Today she is even more active than yesterday and nibbling on hay a bit more, but still way less than what is normal for her. She also accepted today 3 carrot slices, but no paprika.

Has anyone else experience loss of appetite and lethargy after anti-fungal medication? Might be this an adverse effect? This was just her first dosis of anti-fungal meds and she would still have 2 more to go...
Her selectness of the food makes me think of dental problems, but it appeared to soon after the anti-fungal meds to really be a coincidence.
Also, i am not really sure if it is connected to the separation. Two days before she started her meds she was already separated from the other two, due to a possible bond fallout. For those two days she had no possibility to interact with the others and she seems happy, eating hay and enjoying not being chased away constantly by the castrated boar.

Thanks a lot for any tips.

*! All websites related to the medicine listed above are in German.
 
Hi!

I am very sorry, but it is impossible for me to judge whether your piggy has had an adverse reaction to medication, whether it is caused by another underlying issue that is also causing a lowered immune system (skin parasites and fungal are both opportunists that can pop up when a piggy is not well enough to fight off problems) or whether it is a coincidence.
If you are worried about her teeth, please have them checked.

The relatively small amount of weight loss (around 50g) means that your girl has so far still been able to eat a great deal of what she should.

@Jaycey
 
Hi all,

My Muffin started perking up since Monday evening. She is now eating normally and behaving like her usual self.
We don't need to syringe feed her anymore.

On Friday morning I have an appointment t the vet to discuss her reaction and maybe update her medication.
 
Unfortunately my happiness was short lived.
Muffin stopped yesterday afternoon eating and became lethargic once again. I immediately started syringe feeding her again.

At 10 PM I also noticed some bloating, but the belly was still elastic, so the decision was to wait until morning for a vet.
At 2 AM I woke up to feed her again. She was having difficulties even chewing and started having diarrhea. I started soflty massaging her belly with an electric toothbrush, but her situation didn't change.
At 4 AM my husband and I brought her to the emergency room of the veterinary hospital where she will stay for some days.

They have told us that she is bloated and has very little food in her system, but her intenstines are still working, very little but still active. Also her pulse is week and she has lost some fluids.
She was put on infusions and they will try to feed her some more. At 7 AM the doctor will arrive and decide what investigations and meds will she receive.

Please keep your fingers and paws crossed for Muffin
 
So sorry for your loss. You did everything a loving and caring owner could possibly do. Be kind to yourself as you grieve. Sending hugs to you and your other piggies.
Sleep tight little Muffin.xx
 
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