It sounds like their bond is not a happy one.
How old are they?
I would separate them now. Leave them apart for a few days to calm down. Watch the submissive piggy during the separation. If he appears happier to be away from the other then that is usually enough to say their bond is dysfunctional and make the separation permanent. (The dominant piggy will be upset by the separation but it is not his reaction which you go by).
Doing the separation and neutral territory reintroduction gives the piggies a chance to make their own minds up about whether they want to be together.
If during a neutral territory reintroduction tensions rise again then their separation would need to be permanent and they will need to live in separate but side by side cages.
If, however, you can determine now that their bond is not working, then you can just separate them permanently now without attempting to reintroduce them at all. Bullying is a sustained behaviour where the underpig can become withdrawn, lose weight through not being allowed to eat enough, be chased around and not allowed to rest. That is grounds for immediate separation also.
Same applies in the case of an actual fight - do not attempt reintroduction
Piggies who need to live as neighbours each need a cage measuring a minimum of 120x60cm. The cages need to side by side so they can still see, smell, talk to each other and interact between the bars.
Bonds In Trouble
Boars: Teenage, Bullying, Fighting, Fall-outs And What Next?
Dominance Behaviours In Guinea Pigs